{"id":22289,"date":"2026-05-21T11:56:23","date_gmt":"2026-05-21T02:56:23","guid":{"rendered":"https:\/\/www.doochang.co.kr\/blog\/%ec%83%a4%ed%8e%98%eb%a1%a0-%ec%b0%a8%ec%84%b8%eb%8c%80-%eb%a9%b4%ec%97%ad%ed%95%ad%ec%95%94%ec%a0%9c-%ed%8c%8c%ed%95%84%eb%a6%ad%ec%8b%9c%eb%a7%99-%ec%9d%bc%eb%b3%b8-%ed%8a%b9%ed%97%88-%ed%99%95\/"},"modified":"2026-05-21T11:56:23","modified_gmt":"2026-05-21T02:56:23","slug":"%ec%83%a4%ed%8e%98%eb%a1%a0-%ec%b0%a8%ec%84%b8%eb%8c%80-%eb%a9%b4%ec%97%ad%ed%95%ad%ec%95%94%ec%a0%9c-%ed%8c%8c%ed%95%84%eb%a6%ad%ec%8b%9c%eb%a7%99-%ec%9d%bc%eb%b3%b8-%ed%8a%b9%ed%97%88-%ed%99%95","status":"publish","type":"post","link":"https:\/\/www.doochang.co.kr\/blog\/%ec%83%a4%ed%8e%98%eb%a1%a0-%ec%b0%a8%ec%84%b8%eb%8c%80-%eb%a9%b4%ec%97%ad%ed%95%ad%ec%95%94%ec%a0%9c-%ed%8c%8c%ed%95%84%eb%a6%ad%ec%8b%9c%eb%a7%99-%ec%9d%bc%eb%b3%b8-%ed%8a%b9%ed%97%88-%ed%99%95\/","title":{"rendered":"\uc0e4\ud398\ub860 \ucc28\uc138\ub300 \uba74\uc5ed\ud56d\uc554\uc81c \ud30c\ud544\ub9ad\uc2dc\ub9d9 \uc77c\ubcf8 \ud2b9\ud5c8 \ud655\ubcf4\ub85c \uae00\ub85c\ubc8c \uc2dc\uc7a5 \uc9c4\ucd9c \uac00\uc18d\ud654"},"content":{"rendered":"

\uc0e4\ud398\ub860\uc774 \uc790\uc0ac\uc758 \uba74\uc5ed\ud56d\uc554\uc81c \ud6c4\ubcf4\ubb3c\uc9c8 \u2018\ud30c\ud544\ub9ad\uc2dc\ub9d9(Papiliximab)\u2019\uc758 \uc77c\ubcf8 \ud2b9\ud5c8\ub97c \ud655\ubcf4\ud558\uba70 \uae00\ub85c\ubc8c \uc9c0\uc2dd\uc7ac\uc0b0\uad8c \uc804\ub7b5\uc5d0 \ubc15\ucc28\ub97c \uac00\ud558\uace0 \uc788\ub2e4. \uc77c\ubcf8 \ud2b9\ud5c8\uccad(JPO)\uc5d0\uc11c \ud2b9\ud5c8 \ub4f1\ub85d \uacb0\uc815\uc744 \ubc1b\uc740 \uc774\ubc88 \uc131\uacfc\ub294 \ud68c\uc0ac\uc758 IP \ud3ec\ud2b8\ud3f4\ub9ac\uc624\ub97c \uac15\ud654\ud558\uace0 \ud5a5\ud6c4 \uae00\ub85c\ubc8c \uae30\uc220\uc774\uc804 \ubc0f \uacf5\ub3d9 \uac1c\ubc1c \ud611\uc0c1\uc5d0\uc11c\uc758 \ud611\uc0c1\ub825\uc744 \ub192\uc77c \uac83\uc73c\ub85c \uae30\ub300\ub41c\ub2e4.<\/p>\n

\ud30c\ud544\ub9ad\uc2dc\ub9d9\uc740 \ub098\ub178\ub9d9(NanoMab) \ud50c\ub7ab\ud3fc\uc744 \uae30\ubc18\uc73c\ub85c \ud55c \uc774\uc911\ud56d\uccb4(bispecific antibody) \uae30\uc220\ub85c, PD-L1\uacfc CD47\uc744 \ub3d9\uc2dc\uc5d0 \ud45c\uc801\ud558\uace0 \uc788\ub2e4. PD-L1\uc740 T\uc138\ud3ec\uc758 \ud56d\uc554 \uba74\uc5ed\ubc18\uc751\uc744 \uc5b5\uc81c\ud558\ub294 \uba74\uc5ed\uad00\ubb38 \ub2e8\ubc31\uc9c8\ub85c \uc54c\ub824\uc838 \uc788\uc73c\uba70, CD47\uc740 \uc554\uc138\ud3ec\uac00 \ub300\uc2dd\uc138\ud3ec\uc758 \uacf5\uaca9\uc744 \ud68c\ud53c\ud558\ub3c4\ub85d \ub3d5\ub294 \uc2e0\ud638\ub85c \uc54c\ub824\uc838 \uc788\ub2e4. \uc774\ub7ec\ud55c \ub450 \ud45c\uc801\uc744 \ub3d9\uc2dc\uc5d0 \uaca8\ub0e5\ud558\ub294 \ud30c\ud544\ub9ad\uc2dc\ub9d9\uc740 \uc120\ucc9c\uba74\uc5ed\uacfc \ud6c4\ucc9c\uba74\uc5ed\uc744 \ub3d9\uc2dc\uc5d0 \ud65c\uc131\ud654\ud558\ub294 \uac83\uc744 \ubaa9\ud45c\ub85c \ud558\uace0 \uc788\ub2e4.<\/p>\n

\uae00\ub85c\ubc8c \uba74\uc5ed\ud56d\uc554\uc81c \uc2dc\uc7a5\uc5d0\uc11c\ub294 PD-1\u00b7PD-L1 \uc800\ud574\uc81c\uc640 CD47 \ud56d\uccb4\uac00 \uac01\uac01 \uac1c\ubc1c\ub418\uace0 \uc788\uc9c0\ub9cc, \ub2e8\uc77c \ud45c\uc801 \uce58\ub8cc\uc758 \uacbd\uc6b0 \ubc18\uc751\ub960 \ud55c\uacc4\uc640 \ub0b4\uc131 \ubb38\uc81c\uac00 \uc9c0\uc18d\uc801\uc73c\ub85c \uc81c\uae30\ub418\uace0 \uc788\ub2e4. \ud2b9\ud788 CD47 \uacc4\uc5f4 \ud56d\uccb4\ub294 \uc801\ud608\uad6c\uc640\uc758 \uacb0\ud569\uc73c\ub85c \uc778\ud55c \uc6a9\ud608, \ube48\ud608 \ub4f1 \ud608\uc561\ub3c5\uc131\uc774 \uc8fc\uc694 \ubd80\uc791\uc6a9\uc73c\ub85c \uc9c0\uc801\ub418\uace0 \uc788\ub2e4. \uc774\ub7ec\ud55c \ubc30\uacbd \uc18d\uc5d0\uc11c \ucd5c\uadfc\uc5d0\ub294 CD47\uacfc \ub2e4\ub978 \uba74\uc5ed\uad00\ubb38\uc744 \ub3d9\uc2dc\uc5d0 \uaca8\ub0e5\ud558\ub294 \uc774\uc911\ud56d\uccb4 \uae30\uc220\uc774 \uac01\uad11\ubc1b\uace0 \uc788\uc73c\uba70, \uc548\uc804\uc131 \ubc0f \uc57d\uac00 \uce21\uba74\uc5d0\uc11c\uc758 \ubbf8\ucda9\uc871 \uc218\uc694\uac00 \uc5ec\uc804\ud788 \uc874\uc7ac\ud55c\ub2e4.<\/p>\n

\uc0e4\ud398\ub860\uc740 \uc774\ubbf8 PD-L1 \ub2e8\uc77c\ub3c4\uba54\uc778 \ud56d\uccb4, CD47 \ub2e8\uc77c\ub3c4\uba54\uc778 \ud56d\uccb4, PD-L1\u00b7CD47 \uc774\uc911\ud56d\uccb4 \uad6c\uc870\uccb4\uc5d0 \ub300\ud55c \ud2b9\ud5c8\ub97c \ud55c\uad6d, \uc77c\ubcf8, \ud638\uc8fc \ub4f1\uc5d0\uc11c \ud655\ubcf4\ud558\uba70 \uae30\uc220\ub825\uc744 \uc313\uc544\uc654\ub2e4. \uc774\ubc88 \uc77c\ubcf8 \ud2b9\ud5c8 \ub4f1\ub85d\uc740 \ud30c\ud544\ub9ad\uc2dc\ub9d9\uc758 \ud574\uc678 \uc2dc\uc7a5 \uc9c4\uc785\uc744 \uc704\ud55c \uad8c\ub9ac \ubcf4\ud638 \uccb4\uacc4\ub97c \ub354\uc6b1 \uac15\ud654\ud558\ub294 \uc911\uc694\ud55c \uacc4\uae30\uac00 \ub420 \uac83\uc774\ub2e4. \ub610\ud55c, \uc0e4\ud398\ub860\uc740 CD47 \ud45c\uc801 \ud56d\uccb4 \uac1c\ubc1c \uc2dc \uc801\ud608\uad6c\uc640\uc758 \uacb0\ud569\uc744 \ucd5c\uc18c\ud654\ud558\uba74\uc11c\ub3c4 \uc885\uc591 \ubbf8\uc138\ud658\uacbd \ub0b4\uc5d0\uc11c \uc554\uc138\ud3ec\uc640 \uba74\uc5ed\uc138\ud3ec\uc640\uc758 \uacb0\ud569\ub825\uc744 \uc720\uc9c0\ud558\ub3c4\ub85d \ud6c4\ubcf4\ubb3c\uc9c8\uc744 \uc124\uacc4\ud588\ub2e4\uace0 \ubc1d\ud614\ub2e4. \uc774\ub97c \ud1b5\ud574 \uc6d0\uc22d\uc774 \uc804\uc784\uc0c1 \uc2dc\ud5d8\uc5d0\uc11c\ub3c4 \uc2ec\uac01\ud55c \ud608\uc561\ud559\uc801 \uc774\uc0c1 \uc18c\uacac\uc774 \uad00\ucc30\ub418\uc9c0 \uc54a\uc558\uc73c\uba70, \uc885\uc591 \ubaa8\ub378\uc5d0\uc11c\ub3c4 \ub300\uc2dd\uc138\ud3ec \uce68\uc724 \uc99d\uac00 \ubc0f \uc885\uc591 \uc131\uc7a5 \uc5b5\uc81c \ud6a8\uacfc\uac00 \uc785\uc99d\ub418\uc5c8\ub2e4.<\/p>\n

\uc0e4\ud398\ub860\uc740 \ud30c\ud544\ub9ad\uc2dc\ub9d9\uc774 \ub2e8\uc77c \uc57d\uc81c\ub85c T\uc138\ud3ec \uae30\ubc18 \ud6c4\ucc9c\uba74\uc5ed\uacfc \ub300\uc2dd\uc138\ud3ec \uae30\ubc18 \uc120\ucc9c\uba74\uc5ed\uc744 \ub3d9\uc2dc\uc5d0 \ud65c\uc131\ud654\ud558\uba70, \uae30\uc874 CD47 \ud45c\uc801 \ud56d\uccb4 \ubc0f PD-1\u00b7PD-L1 \ub2e8\uc77c \ud56d\uccb4\uc758 \ud55c\uacc4\ub97c \uac1c\uc120\ud560 \uc218 \uc788\uc744 \uac83\uc73c\ub85c \uae30\ub300\ud558\uace0 \uc788\ub2e4. \ud604\uc7ac \ud30c\ud544\ub9ad\uc2dc\ub9d9\uc740 \uc804\uc784\uc0c1 \ub2e8\uacc4\uc5d0 \uc788\uc73c\uba70, \ud68c\uc0ac\ub294 \ubbf8\uad6d, \uc720\ub7fd, \uc911\uad6d \ub4f1 \uc8fc\uc694 \uc2dc\uc7a5\uc5d0\uc11c\uc758 \ud2b9\ud5c8\uad8c \ud655\ub300\ub3c4 \uc9c4\ud589 \uc911\uc774\ub2e4.<\/p>\n

\uc0e4\ud398\ub860\uc758 \uad00\uacc4\uc790\ub294 \u201c\uc774\ubc88 \uc77c\ubcf8 \ud2b9\ud5c8 \ub4f1\ub85d\uc740 \ud30c\ud544\ub9ad\uc2dc\ub9d9\uc758 \ud575\uc2ec \ud45c\uc801\uacfc \uc774\uc911\ud56d\uccb4 \uad6c\uc870\uc5d0 \ub300\ud55c \ud574\uc678 \uad8c\ub9ac \uae30\ubc18\uc744 \uac15\ud654\ud588\ub2e4\ub294 \uc810\uc5d0\uc11c \ub9e4\uc6b0 \uc758\ubbf8\uac00 \ud06c\ub2e4\u201d\uba70, \u201c\uc77c\ubcf8\uc744 \ud3ec\ud568\ud55c \uc544\uc2dc\uc544 \uba74\uc5ed\ud56d\uc554\uc81c \uc2dc\uc7a5\uc758 \ube60\ub978 \uc131\uc7a5\uc138\uc640 \uaddc\uc81c\uae30\uad00\uc758 \ud601\uc2e0 \uce58\ub8cc\uc81c \uc6b0\ub300 \uc815\ucc45\uc744 \uace0\ub824\ud560 \ub54c, \ud30c\ud544\ub9ad\uc2dc\ub9d9\uc740 \uc77c\ubcf8 \ud30c\ud2b8\ub108\uc5d0\uac8c\ub3c4 \uc804\ub7b5\uc801 \uac00\uce58\uac00 \ub192\uc740 \uc790\uc0b0\uc73c\ub85c \ubd80\uac01\ub420 \uac83\u201d\uc774\ub77c\uace0 \ub9d0\ud588\ub2e4.<\/p>\n

[\uad00\ub828\uae30\uc0ac] https:\/\/n.news.naver.com\/mnews\/article\/018\/0006284230?sid=101<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\uc0e4\ud398\ub860\uc774 \uc790\uc0ac\uc758 \uba74\uc5ed\ud56d\uc554\uc81c \ud6c4\ubcf4\ubb3c\uc9c8 \u2018\ud30c\ud544\ub9ad\uc2dc\ub9d9(Papiliximab)\u2019\uc758 \uc77c\ubcf8 \ud2b9\ud5c8\ub97c \ud655\ubcf4\ud558\uba70 \uae00\ub85c\ubc8c \uc9c0\uc2dd\uc7ac\uc0b0\uad8c \uc804\ub7b5\uc5d0 \ubc15\ucc28\ub97c \uac00\ud558\uace0 \uc788\ub2e4. \uc77c\ubcf8 \ud2b9\ud5c8\uccad(JPO)\uc5d0\uc11c \ud2b9\ud5c8 \ub4f1\ub85d \uacb0\uc815\uc744 \ubc1b\uc740 \uc774\ubc88 \uc131\uacfc\ub294 \ud68c\uc0ac\uc758 IP \ud3ec\ud2b8\ud3f4\ub9ac\uc624\ub97c \uac15\ud654\ud558\uace0 \ud5a5\ud6c4 \uae00\ub85c\ubc8c \uae30\uc220\uc774\uc804 \ubc0f \uacf5\ub3d9 \uac1c\ubc1c \ud611\uc0c1\uc5d0\uc11c\uc758 \ud611\uc0c1\ub825\uc744 \ub192\uc77c \uac83\uc73c\ub85c \uae30\ub300\ub41c\ub2e4. \ud30c\ud544\ub9ad\uc2dc\ub9d9\uc740 \ub098\ub178\ub9d9(NanoMab) \ud50c\ub7ab\ud3fc\uc744 \uae30\ubc18\uc73c\ub85c \ud55c \uc774\uc911\ud56d\uccb4(bispecific antibody) \uae30\uc220\ub85c, PD-L1\uacfc CD47\uc744 \ub3d9\uc2dc\uc5d0 \ud45c\uc801\ud558\uace0 \uc788\ub2e4. PD-L1\uc740 T\uc138\ud3ec\uc758 \ud56d\uc554 \uba74\uc5ed\ubc18\uc751\uc744 \uc5b5\uc81c\ud558\ub294 […]<\/p>\n","protected":false},"author":18,"featured_media":66,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_yoast_wpseo_focuskw":"\uc0e4\ud398\ub860","_yoast_wpseo_metadesc":"\uc0e4\ud398\ub860\uc774 \uc77c\ubcf8 \ud2b9\ud5c8\ub97c \ud655\ubcf4\ud558\uba70 \uba74\uc5ed\ud56d\uc554\uc81c \ud30c\ud544\ub9ad\uc2dc\ub9d9\uc758 \uae00\ub85c\ubc8c \uc2dc\uc7a5 \uc9c4\ucd9c\uc744 \uac00\uc18d\ud654\ud558\uace0 \uc788\ub2e4. \uc774 \uc774\uc911\ud56d\uccb4 \uae30\uc220\uc740 PD-L1\uacfc CD47\uc744 \ub3d9\uc2dc\uc5d0 \ud45c\uc801\ud558\uc5ec \uc120\ucc9c\uba74\uc5ed\uacfc \ud6c4\ucc9c\uba74\uc5ed\uc744 \ud65c\uc131\ud654\ud558\ub294 \uac83\uc774 \ubaa9\ud45c\uc774\uba70, \ud608\uc561\ub3c5\uc131 \ubd80\uc791\uc6a9\uc744 \ucd5c\uc18c\ud654\ud558\ub294 \uc124\uacc4\ub85c \uc8fc\ubaa9\ubc1b\uace0 \uc788\ub2e4.","footnotes":""},"categories":[2],"tags":[6039,6199,11631,4262,12599],"class_list":["post-22289","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-2","tag-ai","tag-6199","tag-11631","tag-4262","tag-12599"],"yoast_head":"\n\uc0e4\ud398\ub860 \ucc28\uc138\ub300 \uba74\uc5ed\ud56d\uc554\uc81c \ud30c\ud544\ub9ad\uc2dc\ub9d9 \uc77c\ubcf8 \ud2b9\ud5c8 \ud655\ubcf4\ub85c \uae00\ub85c\ubc8c \uc2dc\uc7a5 \uc9c4\ucd9c \uac00\uc18d\ud654 - \ub450\ucc3d\ud2b9\ud5c8\ubc95\ub960\uc0ac\ubb34\uc18c<\/title>\n<meta name=\"description\" content=\"\uc0e4\ud398\ub860\uc774 \uc77c\ubcf8 \ud2b9\ud5c8\ub97c \ud655\ubcf4\ud558\uba70 \uba74\uc5ed\ud56d\uc554\uc81c \ud30c\ud544\ub9ad\uc2dc\ub9d9\uc758 \uae00\ub85c\ubc8c \uc2dc\uc7a5 \uc9c4\ucd9c\uc744 \uac00\uc18d\ud654\ud558\uace0 \uc788\ub2e4. \uc774 \uc774\uc911\ud56d\uccb4 \uae30\uc220\uc740 PD-L1\uacfc CD47\uc744 \ub3d9\uc2dc\uc5d0 \ud45c\uc801\ud558\uc5ec \uc120\ucc9c\uba74\uc5ed\uacfc \ud6c4\ucc9c\uba74\uc5ed\uc744 \ud65c\uc131\ud654\ud558\ub294 \uac83\uc774 \ubaa9\ud45c\uc774\uba70, \ud608\uc561\ub3c5\uc131 \ubd80\uc791\uc6a9\uc744 \ucd5c\uc18c\ud654\ud558\ub294 \uc124\uacc4\ub85c \uc8fc\ubaa9\ubc1b\uace0 \uc788\ub2e4.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.doochang.co.kr\/blog\/\uc0e4\ud398\ub860-\ucc28\uc138\ub300-\uba74\uc5ed\ud56d\uc554\uc81c-\ud30c\ud544\ub9ad\uc2dc\ub9d9-\uc77c\ubcf8-\ud2b9\ud5c8-\ud655\/\" \/>\n<meta property=\"og:locale\" content=\"ko_KR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\uc0e4\ud398\ub860 \ucc28\uc138\ub300 \uba74\uc5ed\ud56d\uc554\uc81c \ud30c\ud544\ub9ad\uc2dc\ub9d9 \uc77c\ubcf8 \ud2b9\ud5c8 \ud655\ubcf4\ub85c \uae00\ub85c\ubc8c \uc2dc\uc7a5 \uc9c4\ucd9c \uac00\uc18d\ud654 - \ub450\ucc3d\ud2b9\ud5c8\ubc95\ub960\uc0ac\ubb34\uc18c\" \/>\n<meta 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