{"id":4174,"date":"2025-10-07T12:16:09","date_gmt":"2025-10-07T03:16:09","guid":{"rendered":"https:\/\/www.doochang.co.kr\/blog\/%ec%97%90%ec%9d%b4%eb%b9%84%ec%97%98%eb%b0%94%ec%9d%b4%ec%98%a4-4-1bb-%eb%8b%a8%ec%9d%bc%ed%95%ad%ec%b2%b4-%ea%b8%b0%eb%b0%98-%ec%9d%b4%ec%a4%91%ed%95%ad%ec%b2%b4-%ea%b0%9c%eb%b0%9c%eb%a1%9c-%ed%95%ad\/"},"modified":"2025-10-07T12:16:09","modified_gmt":"2025-10-07T03:16:09","slug":"%ec%97%90%ec%9d%b4%eb%b9%84%ec%97%98%eb%b0%94%ec%9d%b4%ec%98%a4-4-1bb-%eb%8b%a8%ec%9d%bc%ed%95%ad%ec%b2%b4-%ea%b8%b0%eb%b0%98-%ec%9d%b4%ec%a4%91%ed%95%ad%ec%b2%b4-%ea%b0%9c%eb%b0%9c%eb%a1%9c-%ed%95%ad","status":"publish","type":"post","link":"https:\/\/www.doochang.co.kr\/blog\/%ec%97%90%ec%9d%b4%eb%b9%84%ec%97%98%eb%b0%94%ec%9d%b4%ec%98%a4-4-1bb-%eb%8b%a8%ec%9d%bc%ed%95%ad%ec%b2%b4-%ea%b8%b0%eb%b0%98-%ec%9d%b4%ec%a4%91%ed%95%ad%ec%b2%b4-%ea%b0%9c%eb%b0%9c%eb%a1%9c-%ed%95%ad\/","title":{"rendered":"\uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624 4-1BB \ub2e8\uc77c\ud56d\uccb4 \uae30\ubc18 \uc774\uc911\ud56d\uccb4 \uac1c\ubc1c\ub85c \ud56d\uc554 \uce58\ub8cc\uc758 \uc0c8\ub85c\uc6b4 \uac00\ub2a5\uc131\uc744 \uc5f4\ub2e4"},"content":{"rendered":"

\uc774\uc911\ud56d\uccb4 \ubd84\uc57c\uc5d0\uc11c \ub450\uac01\uc744 \ub098\ud0c0\ub0b4\uace0 \uc788\ub294 \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uac00 4-1BB \ub2e8\uc77c\ud56d\uccb4\uc640 \uadf8 \uc6a9\ub3c4\uc5d0 \ub300\ud55c \uad6d\ub0b4 \ud2b9\ud5c8\ub97c \ud655\ubcf4\ud588\ub2e4\ub294 \uc18c\uc2dd\uc774 \uc804\ud574\uc84c\ub2e4. \ud574\ub2f9 \ud2b9\ud5c8\ub294 2019\ub144 12\uc6d4 \uad6d\uc81c \ucd9c\uc6d0\ub41c \uc774\ud6c4\ub85c, 2039\ub144\uae4c\uc9c0 \uadf8 \uad8c\ub9ac\uac00 \ubcf4\ud638\ub420 \uc608\uc815\uc774\ub2e4. \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\ub294 \uc774\ubbf8 \ubbf8\uad6d, \uc911\uad6d, \uc77c\ubcf8, \ud638\uc8fc \ub4f1\uc9c0\uc5d0\uc11c 4-1BB \ub2e8\uc77c\ud56d\uccb4 \ud2b9\ud5c8\ub97c \ub4f1\ub85d \uc644\ub8cc\ud588\uc73c\uba70, \uc720\ub7fd \ud2b9\ud5c8\ub294 \ud604\uc7ac \uc2ec\uc0ac \uc911\uc5d0 \uc788\ub2e4.<\/p>\n

4-1BB\ub294 \uc778\uccb4 \uba74\uc5ed \uc2dc\uc2a4\ud15c\uc5d0\uc11c \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 T \uc138\ud3ec\uc758 \ud65c\uc131\ud654\uc5d0 \uad00\uc5ec\ud558\ub294 \ub2e8\ubc31\uc9c8\ub85c, \uc554 \uc138\ud3ec\uc5d0 \ub300\ud55c \uba74\uc5ed \ubc18\uc751\uc744 \uc720\ub3c4\ud558\ub294 \uae30\uc804\uc744 \uac00\uc9c0\uace0 \uc788\ub2e4. T \uc138\ud3ec\uc758 \ud65c\uc131\ud654\ub294 \uc554 \uce58\ub8cc\uc5d0 \uc788\uc5b4 \uc911\uc694\ud55c \uc694\uc18c\ub85c \uc5ec\uaca8\uc9c0\uba70, \ud2b9\ud788 \uc554 \uc138\ud3ec\ub97c \uacf5\uaca9\ud558\ub294 \ub2a5\ub825\uc744 \ub192\uc774\uae30 \uc704\ud574 4-1BB \ub2e8\uc77c\ud56d\uccb4\uac00 \uc8fc\ubaa9\ubc1b\uace0 \uc788\ub2e4. <\/p>\n

\ube0c\ub9ac\uc2a4\ud1a8 \ub9c8\uc774\uc5b4\uc2a4 \uc2a4\ud045(BMS)\uac00 \ucd5c\ucd08\ub85c 4-1BB \ub2e8\uc77c\ud56d\uccb4\ub97c \uac1c\ubc1c\ud588\uc73c\ub098, \uc784\uc0c1 \uc2dc\ud5d8 \uc911 \uc2ec\uac01\ud55c \uac04 \ub3c5\uc131\uc774 \ubc1c\uacac\ub418\uc5b4 \uac1c\ubc1c\uc774 \uc911\ub2e8\ub41c \ubc14 \uc788\ub2e4. \uc774\uc5d0 \ub530\ub77c \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\ub294 4-1BB \ub2e8\uc77c\ud56d\uccb4\uc758 \ud55c\uacc4\ub97c \uadf9\ubcf5\ud558\uae30 \uc704\ud574 \uc774\uc911\ud56d\uccb4 \uad6c\uc870\uc758 ‘\uadf8\ub7a9\ubc14\ub514-T’\ub97c \uac1c\ubc1c\ud588\ub2e4. \uc774\uc911\ud56d\uccb4\ub294 \ud074\ub77c\uc6b0\ub51818.2, HER2\uc640 \uac19\uc740 \uc554 \ud56d\uc6d0\uacfc \uacb0\ud569\ud55c \ud6c4, \uc554 \uc138\ud3ec\uac00 \ubc1c\ud604\ub41c \uc885\uc591\uc758 \ubbf8\uc138\ud658\uacbd\uc5d0\uc11c\ub9cc T \uc138\ud3ec\ub97c \ud65c\uc131\ud654\ud560 \uc218 \uc788\ub3c4\ub85d \uc124\uacc4\ub418\uc5c8\ub2e4. \uc774\ub294 \uae30\uc874 4-1BB \ub2e8\uc77c\ud56d\uccb4\uc758 \ub2e8\uc810\uc744 \ubcf4\uc644\ud558\ub294 \uc911\uc694\ud55c \ubc1c\uc804\uc73c\ub85c \ud3c9\uac00\ub41c\ub2e4.<\/p>\n

\ud604\uc7ac \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\ub294 ABL111(\uc9c0\ubc14\uc2a4\ud1a0\ubbf9), ABL503(\ub77c\uc9c0\uc2a4\ud1a0\ubbf9), ABL103, ABL104(YH32364), ABL105(YH32367) \ub4f1 \uadf8\ub7a9\ubc14\ub514-T \uae30\ubc18\uc758 \uc774\uc911\ud56d\uccb4\ub97c \uc784\uc0c1 \ub2e8\uacc4\uc5d0\uc11c \uac1c\ubc1c\ud558\uace0 \uc788\ub2e4. \ud2b9\ud788 ABL111\uc740 \ubbf8\uad6d\uc5d0\uc11c \ub2c8\ubcfc\ub8e8\ub9d9\uacfc \ud654\ud559\uce58\ub8cc\uc81c\ub97c \ubcd1\uc6a9\ud558\ub294 \uc784\uc0c1 1b\uc0c1\uc744 \uc9c4\ud589 \uc911\uc774\uba70, \ub0b4\ub144 1\ubd84\uae30\uc5d0 \uc784\uc0c1 1b\uc0c1\uc758 \uc6a9\ub7c9 \ud655\uc7a5 \ud30c\ud2b8\uc5d0 \ub300\ud55c \ud0d1\ub77c\uc778 \ub370\uc774\ud130\ub97c \ubc1c\ud45c\ud560 \uc608\uc815\uc774\ub2e4.<\/p>\n

\uc774\uc0c1\ud6c8 \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624 \ub300\ud45c\ub294 \u201c\ucd5c\uadfc \uae30\uc874 \uce58\ub8cc\uc81c\uc640\uc758 \ubcd1\uc6a9\uc744 \ud1b5\ud574 \ud56d\uc554 \ud6a8\ub2a5\uc744 \ub354\uc6b1 \uadf9\ub300\ud654\ud560 \uc218 \uc788\ub3c4\ub85d \uc784\uc0c1 \uc804\ub7b5\uc744 \uc138\uc6cc 4-1BB \uc774\uc911\ud56d\uccb4\ub97c \uac1c\ubc1c \uc911\u201d\uc774\ub77c\uace0 \uc804\ud558\uba70, \u201c\uae30\uc220 \uc774\uc804 \uc0ac\uc5c5\ud654\uc758 \ud544\uc218 \uc694\uc18c\uc778 \ud574\uc678 \ud2b9\ud5c8 \ud655\ubcf4\ub3c4 \uc801\uadf9\uc801\uc73c\ub85c \uc9c4\ud589\ud558\uace0 \uc788\ub2e4\u201d\uace0 \uac15\uc870\ud588\ub2e4. <\/p>\n

\uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uc758 \uc774 \uac19\uc740 \ub178\ub825\uc740 \uc554 \uce58\ub8cc\uc758 \uc0c8\ub85c\uc6b4 \uac00\ub2a5\uc131\uc744 \uc5f4\uace0 \uc788\uc73c\uba70, \uc55e\uc73c\ub85c\uc758 \uc5f0\uad6c\uc640 \uc784\uc0c1 \uacb0\uacfc\uc5d0 \ub530\ub77c \ub9ce\uc740 \ud658\uc790\ub4e4\uc5d0\uac8c \ud76c\ub9dd\uc744 \uc904 \uc218 \uc788\uc744 \uac83\uc73c\ub85c \uae30\ub300\ub41c\ub2e4.<\/p>\n

[\uad00\ub828\uae30\uc0ac] https:\/\/n.news.naver.com\/mnews\/article\/003\/0013507272?sid=102<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\uc774\uc911\ud56d\uccb4 \ubd84\uc57c\uc5d0\uc11c \ub450\uac01\uc744 \ub098\ud0c0\ub0b4\uace0 \uc788\ub294 \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uac00 4-1BB \ub2e8\uc77c\ud56d\uccb4\uc640 \uadf8 \uc6a9\ub3c4\uc5d0 \ub300\ud55c \uad6d\ub0b4 \ud2b9\ud5c8\ub97c \ud655\ubcf4\ud588\ub2e4\ub294 \uc18c\uc2dd\uc774 \uc804\ud574\uc84c\ub2e4. \ud574\ub2f9 \ud2b9\ud5c8\ub294 2019\ub144 12\uc6d4 \uad6d\uc81c \ucd9c\uc6d0\ub41c \uc774\ud6c4\ub85c, 2039\ub144\uae4c\uc9c0 \uadf8 \uad8c\ub9ac\uac00 \ubcf4\ud638\ub420 \uc608\uc815\uc774\ub2e4. \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\ub294 \uc774\ubbf8 \ubbf8\uad6d, \uc911\uad6d, \uc77c\ubcf8, \ud638\uc8fc \ub4f1\uc9c0\uc5d0\uc11c 4-1BB \ub2e8\uc77c\ud56d\uccb4 \ud2b9\ud5c8\ub97c \ub4f1\ub85d \uc644\ub8cc\ud588\uc73c\uba70, \uc720\ub7fd \ud2b9\ud5c8\ub294 \ud604\uc7ac \uc2ec\uc0ac \uc911\uc5d0 \uc788\ub2e4. 4-1BB\ub294 \uc778\uccb4 \uba74\uc5ed \uc2dc\uc2a4\ud15c\uc5d0\uc11c \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 T \uc138\ud3ec\uc758 […]<\/p>\n","protected":false},"author":75,"featured_media":74,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_yoast_wpseo_focuskw":"\uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624","_yoast_wpseo_metadesc":"\uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uac00 4-1BB \ub2e8\uc77c\ud56d\uccb4\uc640 \uadf8 \uc6a9\ub3c4\uc5d0 \ub300\ud55c \uad6d\ub0b4 \ud2b9\ud5c8\ub97c \ud655\ubcf4\ud558\uba70 \uc774\uc911\ud56d\uccb4 '\uadf8\ub7a9\ubc14\ub514-T' \uac1c\ubc1c\uc5d0 \ubc15\ucc28\ub97c \uac00\ud558\uace0 \uc788\ub2e4. \uae30\uc874 \uce58\ub8cc\uc758 \ud55c\uacc4\ub97c \uadf9\ubcf5\ud558\uace0 \uc784\uc0c1\uc5d0\uc11c\uc758 \uc131\uacfc\uac00 \uae30\ub300\ub418\ub294 \uac00\uc6b4\ub370, \uae00\ub85c\ubc8c \uc2dc\uc7a5\uc5d0\uc11c\ub3c4 \ud2b9\ud5c8 \ud655\ubcf4\ub97c \uc801\uadf9 \ucd94\uc9c4\ud558\uace0 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