{"id":8043,"date":"2025-11-21T10:31:29","date_gmt":"2025-11-21T01:31:29","guid":{"rendered":"https:\/\/www.doochang.co.kr\/blog\/%ec%97%90%ec%9d%b4%eb%b9%84%ec%97%98%eb%b0%94%ec%9d%b4%ec%98%a4%ec%9d%98-%ed%94%8c%eb%9e%ab%ed%8f%bc-%ed%98%81%ec%8b%a0%ec%9d%b4-%ec%9d%b4%eb%81%88-%ea%b8%80%eb%a1%9c%eb%b2%8c-%ec%a0%9c%ec%95%bd\/"},"modified":"2025-11-21T10:31:29","modified_gmt":"2025-11-21T01:31:29","slug":"%ec%97%90%ec%9d%b4%eb%b9%84%ec%97%98%eb%b0%94%ec%9d%b4%ec%98%a4%ec%9d%98-%ed%94%8c%eb%9e%ab%ed%8f%bc-%ed%98%81%ec%8b%a0%ec%9d%b4-%ec%9d%b4%eb%81%88-%ea%b8%80%eb%a1%9c%eb%b2%8c-%ec%a0%9c%ec%95%bd","status":"publish","type":"post","link":"https:\/\/www.doochang.co.kr\/blog\/%ec%97%90%ec%9d%b4%eb%b9%84%ec%97%98%eb%b0%94%ec%9d%b4%ec%98%a4%ec%9d%98-%ed%94%8c%eb%9e%ab%ed%8f%bc-%ed%98%81%ec%8b%a0%ec%9d%b4-%ec%9d%b4%eb%81%88-%ea%b8%80%eb%a1%9c%eb%b2%8c-%ec%a0%9c%ec%95%bd\/","title":{"rendered":"\uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uc758 \ud50c\ub7ab\ud3fc \ud601\uc2e0\uc774 \uc774\ub048 \uae00\ub85c\ubc8c \uc81c\uc57d\uc0ac\uc640\uc758 \uacc4\uc57d \uc131\uacfc"},"content":{"rendered":"

\ubc14\uc774\uc624 \ubd84\uc57c\uc5d0\uc11c \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uc758 \ucd5c\uadfc \uc131\uacfc\ub294 \uadf8\uc57c\ub9d0\ub85c \ub208\ubd80\uc2e0 \ubc1c\uc804\uc744 \ubcf4\uc5ec\uc8fc\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud2b9\ud788, \uc77c\ub77c\uc774\ub9b4\ub9ac\uc640\uc758 \uae30\uc220\uc774\uc804 \uacc4\uc57d \uccb4\uacb0\uc740 \uc774 \ud68c\uc0ac\uc758 \ud50c\ub7ab\ud3fc \uae30\uc220\uc774 \uae00\ub85c\ubc8c \uc81c\uc57d \uc2dc\uc7a5\uc5d0\uc11c \uc5b4\ub5bb\uac8c \uc8fc\ubaa9\ubc1b\uace0 \uc788\ub294\uc9c0\ub97c \uc798 \ub098\ud0c0\ub0b4\ub294 \uc0ac\ub840\uc785\ub2c8\ub2e4. \uc774\ubc88 \uacc4\uc57d\uc740 \ub180\ub78d\uac8c\ub3c4 3\uc8708000\uc5b5\uc6d0 \uaddc\ubaa8\ub85c, \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\ub294 \uc774 \uc911 \uc57d 585\uc5b52800\ub9cc\uc6d0\uc744 \uc120\uae09\uae08\uc73c\ub85c \uc218\ub839\ud560 \uc608\uc815\uc785\ub2c8\ub2e4. \uc774\ub294 \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uc758 ‘\uadf8\ub7a9\ubc14\ub514-B’ \ud50c\ub7ab\ud3fc \uae30\uc220\uc774 \uc138\uacc4\uc801\uc73c\ub85c \uc778\uc815\ubc1b\uace0 \uc788\ub2e4\ub294 \uac83\uc744 \ubc29\uc99d\ud558\ub294 \uc911\uc694\ud55c \uc9c0\ud45c\uc785\ub2c8\ub2e4.<\/p>\n

‘\uadf8\ub7a9\ubc14\ub514-B’\ub294 \ub1cc\ud608\uad00\uc7a5\ubcbd(BBB) \ud22c\uacfc \uae30\uc220\ub85c \uc8fc\ubaa9\ubc1b\uace0 \uc788\uc73c\uba70, \uc774\ub294 \uc911\ucd94\uc2e0\uacbd\uacc4(CNS) \uc9c8\ud658 \uce58\ub8cc\uc5d0 \uc788\uc5b4 \uc57d\ubb3c\uc774 \ub1cc\uc5d0 \ub3c4\ub2ec\ud558\ub294 \ub370 \uc788\uc5b4 \uac00\uc7a5 \ud070 \uc7a5\ubcbd\uc73c\ub85c \uc5ec\uaca8\uc9d1\ub2c8\ub2e4. \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\ub294 IGF1R(\uc778\uc290\ub9b0\uc720\uc0ac\uc131\uc7a5\uc778\uc790 1 \uc218\uc6a9\uccb4) \uae30\ubc18\uc758 \uc774\uc911\ud56d\uccb4 \ud50c\ub7ab\ud3fc\uc744 \ud1b5\ud574 \uc774 \ubb38\uc81c\ub97c \ud574\uacb0\ud558\ub824 \ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \uae30\uc220\uc740 \ub1cc \ub0b4 \ub0b4\ud53c\uc138\ud3ec\uc5d0 \uc8fc\ub85c \ubc1c\ud604\ub418\ub294 IGF1R\uc744 \uc154\ud2c0\ub85c \ud65c\uc6a9\ud558\uc5ec \uc57d\ubb3c\uc774 \ud608\ub958\ub97c \ub118\uc5b4 \ub1cc \uc870\uc9c1 \uae4a\uc219\uc774 \ub3c4\ub2ec\ud560 \uc218 \uc788\ub3c4\ub85d \ub3d5\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud2b9\ud788 \ube44\uc784\uc0c1 \uc2dc\ud5d8\uc5d0\uc11c\ub294 ‘\uadf8\ub7a9\ubc14\ub514-B’\ub97c \uc801\uc6a9\ud55c \ud6c4\ubcf4\ubb3c\uc9c8\uc774 \uae30\uc874 \ub2e8\uc77c\ud56d\uccb4\ubcf4\ub2e4 \uc57d 13\ubc30 \ub192\uc740 \ub1cc \ub0b4 \uce68\ud22c\ub825\uc744 \ubcf4\uc600\uc73c\uba70, \uc57d\ubb3c \ub18d\ub3c4\ub97c \uc7a5\uc2dc\uac04 \uc548\uc815\uc801\uc73c\ub85c \uc720\uc9c0\ud558\ub294 \uc131\uacfc\ub97c \ub098\ud0c0\ub0c8\uc2b5\ub2c8\ub2e4. \ub610\ud55c \ub3c5\uc131 \uc9c0\ud45c\uc5d0\uc11c\ub3c4 \uc6b0\uc218\ud55c \uc548\uc804\uc131\uc744 \ud655\ubcf4\ud55c \uac83\uc73c\ub85c \ud3c9\uac00\ubc1b\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uac00 \uae30\uc220\ub825\uc744 \ubc14\ud0d5\uc73c\ub85c \ub2e4\uc591\ud55c CNS \uc9c8\ud658\uc5d0 \ub300\ud55c \uce58\ub8cc\uc81c\ub97c \uac1c\ubc1c\ud560 \uc218 \uc788\ub294 \uac00\ub2a5\uc131\uc744 \ubcf4\uc5ec\uc8fc\ub294 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

\uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uc758 \ub204\uc801 \uae30\uc220\uc774\uc804 \uaddc\ubaa8\ub294 \uc774\ubc88 \uacc4\uc57d\uc744 \ud3ec\ud568\ud574 \ucd1d 11\uc870\uc6d0\uc744 \ub118\uc5b4\uc130\uc2b5\ub2c8\ub2e4. \uc774 \ud68c\uc0ac\ub294 2018\ub144 \uc720\ud55c\uc591\ud589\uc5d0 \ud56d\uc554 \ud30c\uc774\ud504\ub77c\uc778 ABL101\uacfc ABL105\ub97c 590\uc5b5\uc6d0\uc5d0 \uc774\uc804\ud55c \uac83\uc744 \uc2dc\uc791\uc73c\ub85c, \ubbf8\uad6d\uc758 \ucf64\ud30c\uc2a4 \ud14c\ub77c\ud4e8\ud2f1\uc2a4\uc5d0 \ud56d\uc554 \ud6c4\ubcf4\ubb3c\uc9c8 ABL001\uc744 7900\uc5b5\uc6d0\uc5d0, \uc911\uad6d\uc758 \uc528\uc2a4\ud1a4 \ud30c\ub9c8\uc288\ud2f0\uceec\uc2a4\uc5d0 ABL202\ub97c 4800\uc5b5\uc6d0\uc5d0 \uc218\ucd9c\ud558\uba70 \uae30\uc220\uc774\uc804\uc744 \ud655\ub300\ud574\uc654\uc2b5\ub2c8\ub2e4. \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\ub294 \ud2b9\ud788 \uadf8\ub7a9\ubc14\ub514-B \uae30\uc220\uc744 \uc911\uc2ec\uc73c\ub85c \ub2e4\uc591\ud55c \uacc4\uc57d\uc744 \uc131\uc0ac\uc2dc\ud0a4\uba70 \uadf8 \uae30\uc220\ub825\uc744 \uc785\uc99d\ud574\uc654\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc62c\ud574 4\uc6d4\uc5d0\ub294 \uc601\uad6d\uc758 GSK\uc5d0 \uadf8\ub7a9\ubc14\ub514-B \uae30\uc220\uc744 4\uc8701200\uc5b5\uc6d0\uc5d0 \uc774\uc804\ud558\uba70 \ub2e4\uc2dc \ud55c\ubc88 \uae30\uc220\ub825\uc744 \uacfc\uc2dc\ud558\uc600\uace0, \uc774\ubc88 \uc77c\ub77c\uc774\ub9b4\ub9ac\uc640\uc758 \uacc4\uc57d\uc740 \uae00\ub85c\ubc8c \uc81c\uc57d\uc0ac\uc640\uc758 \uc5f0\uc18d\uc801\uc778 \uc131\uacf5 \uc0ac\ub840\ub85c \uae30\ub85d\ub420 \uac83\uc785\ub2c8\ub2e4. \uc774\ub294 \ub2e8\uc77c \ud50c\ub7ab\ud3fc\uc73c\ub85c \uc5f0\uc774\uc5b4 \uacc4\uc57d\uc744 \uc131\uc0ac\uc2dc\ud0a8 \ub9e4\uc6b0 \ub4dc\ubb38 \uc0ac\ub840\ub85c, \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uc758 \uae30\uc220\ub825\uc774 \ube44\uc57d\uc801\uc73c\ub85c \ubc1c\uc804\ud558\uace0 \uc788\ub2e4\ub294 \uac83\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4.<\/p>\n

\uc5c4\ubbfc\uc6a9 \uc2e0\ud55c\ud22c\uc790\uc99d\uad8c \uc5f0\uad6c\uc6d0\uc740 \uc774\ubc88 \uacc4\uc57d\uc5d0 \ub300\ud574 \uc8fc\ubaa9\ud560 \ub9cc\ud55c \ud3c9\uac00\ub97c \ub0b4\ub193\uc558\uc2b5\ub2c8\ub2e4. \uadf8\ub294 ‘\ub9b4\ub9ac\ub294 \ube44\ub9cc\uc57d \uc678\uc5d0\ub3c4 \ud1f4\ud589\uc131 \ub1cc\uc9c8\ud658 \uce58\ub8cc\uc81c\ub97c \uac1c\ubc1c \uc911\uc778 \uae30\uc5c5\uc73c\ub85c, \uc5d0\uc774\ube44\uc5d8\uc758 \ub1cc\ud22c\uacfc \uc154\ud2c0 \ub3c4\uc785 \uac00\ub2a5\uc131\uc774 \uac00\uc7a5 \uc8fc\ubaa9\ubc1b\ub358 \uacf3’\uc774\ub77c\uba70 ‘\uadf8\ub7a9\ubc14\ub514-B\ub97c \ud1b5\ud574 \uae30\uc874 \uc57d\ubb3c\uc758 \ubd80\uc791\uc6a9 \ud55c\uacc4\ub97c \ubcf4\uc644\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub41c\ub2e4’\uace0 \ubd84\uc11d\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub610\ud55c \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\ub294 \uc77c\ub77c\uc774\ub9b4\ub9ac\uc640 220\uc5b5\uc6d0 \uaddc\ubaa8\uc758 \uc9c0\ubd84 \ud22c\uc790 \uacc4\uc57d\ub3c4 \uccb4\uacb0\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uadf8\ub7a9\ubc14\ub514-B \uae30\uc220\uc774\uc804 \uacc4\uc57d\uc758 \ud6c4\uc18d \uc870\uce58\ub85c \ud574\uc11d\ub418\uba70, \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\ub294 \uc8fc\ub2f9 12\ub9cc5900\uc6d0\uc5d0 \uc2e0\uc8fc 17\ub9cc5079\uc8fc\ub97c \ubc1c\ud589\ud558\uac8c \ub429\ub2c8\ub2e4. \uc774\ub294 \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uc758 \uc9c0\uc18d\uc801\uc778 \uae30\uc220 \ubc1c\uc804\uacfc \uae00\ub85c\ubc8c \uc2dc\uc7a5\uc5d0\uc11c\uc758 \uc785\uc9c0\ub97c \ub354\uc6b1 \ud655\uace0\ud788 \ud558\uae30 \uc704\ud55c \uc804\ub7b5\uc73c\ub85c \ubcfc \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uacb0\ub860\uc801\uc73c\ub85c, \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uc758 ‘\uadf8\ub7a9\ubc14\ub514-B’ \ud50c\ub7ab\ud3fc \uae30\uc220\uc740 \uc911\ucd94\uc2e0\uacbd\uacc4 \uc9c8\ud658 \uce58\ub8cc\uc5d0 \uc788\uc5b4 \ud68d\uae30\uc801\uc778 \uac00\ub2a5\uc131\uc744 \ubcf4\uc5ec\uc8fc\uace0 \uc788\uc73c\uba70, \uc774\ub97c \ubc14\ud0d5\uc73c\ub85c \uae00\ub85c\ubc8c \uc81c\uc57d\uc0ac\ub4e4\uacfc\uc758 \ud611\ub825\uc774 \uacc4\uc18d\ud574\uc11c \uc774\uc5b4\uc9c8 \uac83\uc73c\ub85c \uc804\ub9dd\ub429\ub2c8\ub2e4. \uc55e\uc73c\ub85c\uc758 \ud589\ubcf4\uac00 \ub354\uc6b1 \uae30\ub300\ub418\ub294 \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uc758 \ubbf8\ub798\ub97c \uc8fc\ubaa9\ud574 \ubd10\uc57c \ud560 \uc2dc\uc810\uc785\ub2c8\ub2e4.<\/p>\n

[\uad00\ub828\uae30\uc0ac] https:\/\/n.news.naver.com\/mnews\/article\/031\/0000981337?sid=101<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\ubc14\uc774\uc624 \ubd84\uc57c\uc5d0\uc11c \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uc758 \ucd5c\uadfc \uc131\uacfc\ub294 \uadf8\uc57c\ub9d0\ub85c \ub208\ubd80\uc2e0 \ubc1c\uc804\uc744 \ubcf4\uc5ec\uc8fc\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud2b9\ud788, \uc77c\ub77c\uc774\ub9b4\ub9ac\uc640\uc758 \uae30\uc220\uc774\uc804 \uacc4\uc57d \uccb4\uacb0\uc740 \uc774 \ud68c\uc0ac\uc758 \ud50c\ub7ab\ud3fc \uae30\uc220\uc774 \uae00\ub85c\ubc8c \uc81c\uc57d \uc2dc\uc7a5\uc5d0\uc11c \uc5b4\ub5bb\uac8c \uc8fc\ubaa9\ubc1b\uace0 \uc788\ub294\uc9c0\ub97c \uc798 \ub098\ud0c0\ub0b4\ub294 \uc0ac\ub840\uc785\ub2c8\ub2e4. \uc774\ubc88 \uacc4\uc57d\uc740 \ub180\ub78d\uac8c\ub3c4 3\uc8708000\uc5b5\uc6d0 \uaddc\ubaa8\ub85c, \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\ub294 \uc774 \uc911 \uc57d 585\uc5b52800\ub9cc\uc6d0\uc744 \uc120\uae09\uae08\uc73c\ub85c \uc218\ub839\ud560 \uc608\uc815\uc785\ub2c8\ub2e4. \uc774\ub294 \uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uc758 ‘\uadf8\ub7a9\ubc14\ub514-B’ \ud50c\ub7ab\ud3fc \uae30\uc220\uc774 \uc138\uacc4\uc801\uc73c\ub85c \uc778\uc815\ubc1b\uace0 \uc788\ub2e4\ub294 \uac83\uc744 \ubc29\uc99d\ud558\ub294 \uc911\uc694\ud55c \uc9c0\ud45c\uc785\ub2c8\ub2e4. ‘\uadf8\ub7a9\ubc14\ub514-B’\ub294 \ub1cc\ud608\uad00\uc7a5\ubcbd(BBB) […]<\/p>\n","protected":false},"author":89,"featured_media":70,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_yoast_wpseo_focuskw":"\uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624","_yoast_wpseo_metadesc":"\uc5d0\uc774\ube44\uc5d8\ubc14\uc774\uc624\uac00 \uc77c\ub77c\uc774\ub9b4\ub9ac\uc640 \uccb4\uacb0\ud55c 3\uc8708000\uc5b5\uc6d0 \uaddc\ubaa8\uc758 \uae30\uc220\uc774\uc804 \uacc4\uc57d\uc740 \uadf8\ub7a9\ubc14\ub514-B \ud50c\ub7ab\ud3fc \uae30\uc220\uc758 \uae00\ub85c\ubc8c \uc2dc\uc7a5 \uac00\uce58\uac00 \uc778\uc815\ubc1b\uc558\uc74c\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. \uc774 \ud50c\ub7ab\ud3fc\uc740 \ub1cc\ud608\uad00\uc7a5\ubcbd\uc744 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